- At the end of the film we see the singer Marilyn Manson in a small role as a Pornstar.
- It all started with the expression "Lost highway" (Lost Highway), Lynch read in the mouth of one of the characters in the book by Barry Gifford “Night People”. From the evocative phrase, and some other thoughts his, Lynch planned to write something with the author.
- Lynch included an anecdote that happened really: Someone called the Bell of his house and said: «Dave, Dick Laurant is dead» and although Lynch, that was never to know who spoke or who was Laurant, He has made it clear that one of his neighbors was an actor named David Landers and, Therefore, all may have been a simple confusion.
Thanks to Albert Perez. Extracted from www.tepasmas.com and www.miradas.net